On average, the Sato Racing slip-on exhaust will boost your Yamaha's hosepower by 5-10 on the top end of your power curve. Weighin in at half the weight of your stock exhaust, you're shaving off 9 lbs of the end of your bike by going with a Sato system.
Note: The 2006 R6S uses the Slip-On System from the 2003-05 R6